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The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect.
Amanzio, Martina; Cipriani, Giuseppina Elena; Mitsikostas, Dimos D.
  • Amanzio M; Department of Psychology, University of Turin, Turin, Italy.
  • Cipriani GE; Department of Psychology, University of Turin, Turin, Italy.
  • Mitsikostas DD; First Department of Neurology, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Expert Rev Clin Pharmacol ; 15(12): 1377-1382, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2087632
ABSTRACT

INTRODUCTION:

The COVID-19 pandemic had remarkable effects on psychological distress. The main stressors were prolonged quarantine and social isolation, fear of infection and death, stigmatization, infodemic, financial difficulties, and job loss. These negative stressors, which affect mental and physical health, make people more vulnerable to nocebo-related risk behaviors. We aimed to summarize data on nocebo behaviors, such as the negative psychological consequences of the COVID-19 pandemic in terms of how people perceive and interpret medical services and treatments. AREAS COVERED Limited data were found from randomized controlled trials with SARS-CoV-2 vaccines and from surveys on healthy people, healthcare workers, and patients with chronic pain disorders. EXPERT OPINION Studies have shown nocebo effects among participants in SARS-CoV-2 vaccines trials, among patients with chronic pain, and among healthcare workers. These effects were widely amplified during the pandemic era, prefiguring a 'nocebodemic effect' to describe the massive negative interpretation of health services and medical treatments. Greater awareness of these findings could reduce the impact of the 'nocebodemic effect' and increase public trust in science.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Chronic Pain / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Expert Rev Clin Pharmacol Year: 2022 Document Type: Article Affiliation country: 17512433.2022.2142115

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Chronic Pain / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Expert Rev Clin Pharmacol Year: 2022 Document Type: Article Affiliation country: 17512433.2022.2142115