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Estimating the Effectiveness of Shielding during Pregnancy against SARS-CoV-2 in New York City during the First Year of the COVID-19 Pandemic.
Chen, Siyu; Murphy, Elisabeth A; Pendergrass, Angeline G; Sukhu, Ashley C; Eng, Dorothy; Jurkiewicz, Magdalena; Mohammed, Iman; Rand, Sophie; White, Lisa J; Hupert, Nathaniel; Yang, Yawei J.
  • Chen S; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX1 3QD, UK.
  • Murphy EA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Pendergrass AG; Department of Earth and Atmospheric Sciences, Cornell University, Ithaca, NY 14853, USA.
  • Sukhu AC; New York Presbyterian-Weill Cornell Medicine, New York, NY 10065, USA.
  • Eng D; New York Presbyterian-Weill Cornell Medicine, New York, NY 10065, USA.
  • Jurkiewicz M; New York Presbyterian-Weill Cornell Medicine, New York, NY 10065, USA.
  • Mohammed I; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA.
  • Rand S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • White LJ; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX1 3QD, UK.
  • Hupert N; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX1 3QD, UK.
  • Yang YJ; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY 10065, USA.
Viruses ; 14(11)2022 Oct 30.
Article in English | MEDLINE | ID: covidwho-2090370
ABSTRACT
Pregnant patients have increased morbidity and mortality in the setting of SARS-CoV-2 infection. The exposure of pregnant patients in New York City to SARS-CoV-2 is not well understood due to early lack of access to testing and the presence of asymptomatic COVID-19 infections. Before the availability of vaccinations, preventative (shielding) measures, including but not limited to wearing a mask and quarantining at home to limit contact, were recommended for pregnant patients. Using universal testing data from 2196 patients who gave birth from April through December 2020 from one institution in New York City, and in comparison, with infection data of the general population in New York City, we estimated the exposure and real-world effectiveness of shielding in pregnant patients. Our Bayesian model shows that patients already pregnant at the onset of the pandemic had a 50% decrease in exposure compared to those who became pregnant after the onset of the pandemic and to the general population.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Female / Humans / Pregnancy Country/Region as subject: North America Language: English Year: 2022 Document Type: Article Affiliation country: V14112408

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Vaccines Limits: Female / Humans / Pregnancy Country/Region as subject: North America Language: English Year: 2022 Document Type: Article Affiliation country: V14112408