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Safety and Immunogenicity of Intradermal Fractional Dose Administration of the mRNA-1273 Vaccine: A Proof-of-Concept Study.
Roozen, Geert V T; Prins, Margaretha L M; van Binnendijk, Rob; den Hartog, Gerco; Kuiper, Vincent P; Prins, Corine; Janse, Jacqueline J; Kruithof, Annelieke C; Feltkamp, Mariet C W; Kuijer, Marjan; Rosendaal, Frits R; Roestenberg, Meta; Visser, Leo G; Roukens, Anna H E.
  • Roozen GVT; Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands (G.V.R., M.L.P., C.P., L.G.V., A.H.R.).
  • Prins MLM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands (G.V.R., M.L.P., C.P., L.G.V., A.H.R.).
  • van Binnendijk R; Department of Immune Surveillance, National Institute for Public Health and the Environment, Bilthoven, the Netherlands (R.V., G.D., M.K.).
  • den Hartog G; Department of Immune Surveillance, National Institute for Public Health and the Environment, Bilthoven, the Netherlands (R.V., G.D., M.K.).
  • Kuiper VP; Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands (V.P.K., J.J.J.).
  • Prins C; Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands (G.V.R., M.L.P., C.P., L.G.V., A.H.R.).
  • Janse JJ; Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands (V.P.K., J.J.J.).
  • Kruithof AC; Department of Infectious Diseases, Leiden University Medical Center, and Centre for Human Drug Research, Leiden, the Netherlands (A.C.K.).
  • Feltkamp MCW; Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands (M.C.F.).
  • Kuijer M; Department of Immune Surveillance, National Institute for Public Health and the Environment, Bilthoven, the Netherlands (R.V., G.D., M.K.).
  • Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands (F.R.R.).
  • Roestenberg M; Department of Infectious Diseases and Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands (M.R.).
  • Visser LG; Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands (G.V.R., M.L.P., C.P., L.G.V., A.H.R.).
  • Roukens AHE; Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands (G.V.R., M.L.P., C.P., L.G.V., A.H.R.).
Ann Intern Med ; 2022 Oct 25.
Article in English | MEDLINE | ID: covidwho-2090819

Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines Language: English Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines Language: English Year: 2022 Document Type: Article