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Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities.
Rajabi, Hadi; Mortazavi, Deniz; Konyalilar, Nur; Aksoy, Gizem Tuse; Erkan, Sinem; Korkunc, Seval Kubra; Kayalar, Ozgecan; Bayram, Hasan; Rahbarghazi, Reza.
  • Rajabi H; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey.
  • Mortazavi D; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey.
  • Konyalilar N; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey.
  • Aksoy GT; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey.
  • Erkan S; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey.
  • Korkunc SK; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey.
  • Kayalar O; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey.
  • Bayram H; Koç University Research Centre for Translational Medicine (KUTTAM), Koç University School of Medicine, Istanbul, Turkey. habayram@ku.edu.tr.
  • Rahbarghazi R; Department of Pulmonary Medicine, School of Medicine, Koç University, Istanbul, Turkey. habayram@ku.edu.tr.
Cell Commun Signal ; 20(1): 173, 2022 11 01.
Article in English | MEDLINE | ID: covidwho-2098351
ABSTRACT
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been growing swiftly worldwide. Patients with background chronic pulmonary inflammations such as asthma or chronic obstructive pulmonary diseases (COPD) are likely to be infected with this virus. Of note, there is an argument that COVID-19 can remain with serious complications like fibrosis or other pathological changes in the pulmonary tissue of patients with chronic diseases. Along with conventional medications, regenerative medicine, and cell-based therapy could be alternative approaches to compensate for organ loss or restore injured sites using different stem cell types. Owing to unique differentiation capacity and paracrine activity, these cells can accelerate the healing procedure. In this review article, we have tried to scrutinize different reports related to the harmful effects of SARS-CoV-2 on patients with asthma and COPD, as well as the possible therapeutic effects of stem cells in the alleviation of post-COVID-19 complications. Video abstract.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Asthma / Pulmonary Disease, Chronic Obstructive / COVID-19 Topics: Long Covid Limits: Humans Language: English Journal: Cell Commun Signal Year: 2022 Document Type: Article Affiliation country: S12964-022-00982-5

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Asthma / Pulmonary Disease, Chronic Obstructive / COVID-19 Topics: Long Covid Limits: Humans Language: English Journal: Cell Commun Signal Year: 2022 Document Type: Article Affiliation country: S12964-022-00982-5