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Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia.
Zhang, Tongqiang; Cui, Xiaojian; Zhao, Xue; Wang, Jinhu; Zheng, Jiafeng; Zheng, Guifen; Guo, Wei; Cai, Chunquan; He, Sijia; Xu, Yongsheng.
  • Zhang T; Department of Respiratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
  • Cui X; Graduate School of Tianjin Medical University, Tianjin, China.
  • Zhao X; Department of Clinical Laboratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
  • Wang J; Department of Clinical Laboratory, Shenyang Coloproctology Hospital, Liaoning, China.
  • Zheng J; Department of Neonatal Surgery, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
  • Zheng G; Department of Respiratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
  • Guo W; Department of Imaging, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
  • Cai C; Department of Respiratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
  • He S; Department of Neurosurgery, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
  • Xu Y; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia.
J Med Virol ; 92(7): 909-914, 2020 07.
Article in English | MEDLINE | ID: covidwho-21003
ABSTRACT
Coronavirus Disease 2019 (COVID-19) is a newly emerging infectious disease caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). After its first occurrence in Wuhan of China from December 2019, COVID-19 rapidly spread around the world. According to the World Health Organization statement on 13 March 2020, there had been over 132 500 confirmed cases globally. Nevertheless, the case reports of children are rare, which results in the lack of evidence for preventing and controlling of children's infection. Here, we report three cases of SARS-CoV-2 infected children diagnosed from 3 February to 17 February 2020 in Tianjin, China. All of these three cases experienced mild illness and recovered soon after the treatment, with the nucleic acid of throat swab turning negative within 14, 11, and 7 days after diagnosis, respectively. However, after been discharged, all three cases were tested SARS-CoV-2 positive in the stool samples within 10 days, in spite of their remained negative nucleic acid in throat swab specimens. Therefore, it is necessary to be aware of the possibility of fecal-oral transmission of SARS-CoV-2 infection, especially for children cases.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / RNA, Viral / Convalescence / Coronavirus Infections / Clinical Laboratory Techniques / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Topics: Traditional medicine Limits: Child / Humans / Male Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2020 Document Type: Article Affiliation country: Jmv.25795

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / RNA, Viral / Convalescence / Coronavirus Infections / Clinical Laboratory Techniques / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Topics: Traditional medicine Limits: Child / Humans / Male Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2020 Document Type: Article Affiliation country: Jmv.25795