Infections with Herpes simplex and Varicella zoster virus.
J Dtsch Dermatol Ges
; 20(10): 1327-1351, 2022 10.
Article
in English
| MEDLINE | ID: covidwho-2103148
ABSTRACT
Human herpes viruses belong to the DNA viruses and are among the most common viral pathogens. Currently, eight human herpes viruses have been characterized. Primary infection is typically followed by virus latency. Viral reactivations are more often symptomatic than primary infections and lead more often to medical consultation. In daily practice, infections with herpes simplex virus (HSV) and varicella zoster virus (VZV) are the most common. If HSV primary infections become clinically manifest, they are often accompanied by systemic symptoms whereas manifest HSV reactivations are usually harmless, self-limiting and present as grouped vesicles on an erythematous base (herpetiform). Primary VZV infection leads to the clinical picture of varicella (chickenpox). VZV reactivation manifests clinically as shingles and can be accompanied by severe acute neuralgiform pain. In immunosuppression, complicated (necrotizing, ulcerative, hemorrhagic, generalized) manifestations may occur. The diagnosis is usually made clinically. Therapeutic options include topical agents and systemic antivirals. Adequate therapeutic management includes the recognition and treatment of complications such as the possible involvement of other organ systems and pain. Infection during pregnancy may result in transmission to the unborn child.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Chickenpox
/
Herpes Simplex
/
Herpes Zoster
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
J Dtsch Dermatol Ges
Journal subject:
Dermatology
Year:
2022
Document Type:
Article
Affiliation country:
Ddg.14917
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