Molecular typing and epidemiology profiles of human adenovirus infection among children with severe acute respiratory infection in Huzhou, China.
Lett Appl Microbiol
; 75(5): 1225-1231, 2022 Nov.
Article
in English
| MEDLINE | ID: covidwho-2103163
ABSTRACT
Human adenoviruses (HAdVs) are prevalent worldwide and are a common cause of respiratory tract infection in people of all ages. However, little is known about HAdV infection among children with severe acute respiratory infection (SARI). The present study retrospectively analysed the molecular typing and epidemiological characteristics of HAdV-positive samples from children with SARI from January 2017 to December 2021 in Huzhou. The results showed that 89 (8·27%) of 1078 SARI paediatric patients were positive for HAdVs. Children <5 years of age accounted for 87·64% of the positive cases. The peak seasons for HAdV infection were the first quarter and the fourth quarter. In addition, HAdV-B and HAdV-C were circulating among paediatric patients with SARI, of which the B3 genotype (n = 30, 51·72%) was the most prevalent and was detected every year, indicating that B3 is the main epidemic strain in the Huzhou area, followed by C1 (n = 9, 15·52%), C2 (n = 7, 12·07%) and B7 (n = 5, 8·62%). These findings provide a benchmark for future epidemiology and prevention strategies for HAdVs.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia
/
Respiratory Tract Infections
/
Adenovirus Infections, Human
/
Adenoviruses, Human
Type of study:
Observational study
/
Randomized controlled trials
Limits:
Child
/
Humans
/
Infant
Country/Region as subject:
Asia
Language:
English
Journal:
Lett Appl Microbiol
Journal subject:
Microbiology
Year:
2022
Document Type:
Article
Affiliation country:
Lam.13790
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