Emergence of SARS-CoV-2 Omicron variant and strategies for tackling the infection.
Immun Inflamm Dis
; 10(12): e733, 2022 Dec.
Article
in English
| MEDLINE | ID: covidwho-2103565
ABSTRACT
INTRODUCTION:
Nowadays, emerging SARS-CoV-2 Omicron, the novel highly mutated VOC, has quickly spread as the dominant variant in over 190 countries worldwide through the first part of 2022, which is influencing the infectivity, transmissibility, pathogenicity, and severity of COVID-19 pandemic. Additionally, clinical cases and experimental studies have reported that Omicron variant likely leads to weakened immune protection elicited by infection, antibody therapies, and vaccines. The new wave, from late February, 2022, was escalated abruptly by higher levels of transmission of Omicron BA.2 sublineage in China. METHODS ANDRESULTS:
Following a systematic database search, this review summarizes the salient features of Omicron sublineages, and their impact on transmissibility, disease severity as well as the efficacy of the available vaccines and treatment against the Omicron.CONCLUSION:
We hope this study will provide a scientific reference for alleviating the burden of COVID-19.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Prognostic study
/
Reviews
/
Systematic review/Meta Analysis
Topics:
Vaccines
/
Variants
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Immun Inflamm Dis
Year:
2022
Document Type:
Article
Affiliation country:
Iid3.733
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