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Myocardial infarction following COVID-19 vaccine administration; a systematic review.
Baqi, Dana H; Kakamad, Fahmi H; Mahmood, Zana H; Fattah, Fattah H; Ahmed, Shaho F; Hassan, Marwan N; Hama Amin, Bnar J; Mohammed, Shvan H; Mikael, Tomas M; Hassan, Hunar A; Salh, Abdulwahid M.
  • Baqi DH; Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
  • Kakamad FH; College of Medicine, University of Sulaimani, Sulaimani, Kurdistan, Iraq.
  • Mahmood ZH; Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
  • Fattah FH; College of Medicine, University of Sulaimani, Sulaimani, Kurdistan, Iraq.
  • Ahmed SF; Kscien Organization, Hamdi Str., Azadi Mall, Sulaimani, Kurdistan, Iraq.
  • Hassan MN; Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
  • Hama Amin BJ; Molecular Diagnostic Laboratory, Sulaimani Veterinary Directorate, Sulaimani, Kurdistan, Iraq.
  • Mohammed SH; Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
  • Mikael TM; College of Medicine, University of Sulaimani, Sulaimani, Kurdistan, Iraq.
  • Hassan HA; Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
  • Salh AM; Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
Heliyon ; 8(11): e11385, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2179016
ABSTRACT

Introduction:

Covid-19 vaccines have been assessed in randomized trials, which are designed to establish efficacy and safety, but are insufficient in power to detect rare adverse outcomes. Among the adverse cardiac events associated with mRNA COVID-19 vaccines are inflammations (e.g., pericarditis or myocarditis), thrombosis, and ischemia.

Objective:

This systematic review aims to evaluate the reported cases of myocardial infarction (MI) after COVID-19 vaccinations.

Method:

Web of Science, MEDLINE on OVID, PubMed, and Google Scholar were searched for English-language papers published until March 25, 2022.

Results:

This study included 15 papers (10 case reports and 5 case series). In total, 20 individuals were included who had received COVID-19 vaccines and experienced MI. Males (55%) reported more adverse occurrences than females (45%) across the majority of event categories. The mean time from the administration of the vaccine to the onset of symptoms was 2 days (0-10 days). The AstraZeneca vaccine was responsible for more than half of the reported events. In the majority of cases, the event developed after receiving the first dose of vaccination.

Conclusion:

MI related to COVID19 vaccination is a rare, but serious and life-threatening condition. Chest discomfort should be regarded as a warning sign, particularly in people who have been administered a dose of the vaccine within the previous two days.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Randomized controlled trials / Reviews / Systematic review/Meta Analysis Topics: Vaccines Language: English Journal: Heliyon Year: 2022 Document Type: Article Affiliation country: J.heliyon.2022.e11385

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Randomized controlled trials / Reviews / Systematic review/Meta Analysis Topics: Vaccines Language: English Journal: Heliyon Year: 2022 Document Type: Article Affiliation country: J.heliyon.2022.e11385