Individual and household risk factors for COVID-19 infection among household members of COVID-19 patients in home-based care in western Uganda, 2020.
IJID Reg
; 5: 183-190, 2022 Dec.
Article
in English
| MEDLINE | ID: covidwho-2105102
ABSTRACT
Objective:
To investigate factors associated with COVID-19 among household members of patients in home-based care (HBC) in western Uganda.Methods:
We conducted a case-control and cohort study. Cases were reverse transcriptase-polymerase chain reaction-confirmed SARS-CoV-2 diagnosed 1-30 November 2020 among persons in HBC in Kasese or Kabarole districts. We compared 78 case-households (≥1 secondary case) with 59 control-households (no secondary cases). The cohort included all case-household members. Data were captured by in-person questionnaire. We used bivariate regression to calculate odds and risk ratios.Results:
Case-households were larger than control-households (mean 5.8 vs 4.3 members, P<0.0001). Having ≥1 household member per room (adjusted odds ratio (aOR)=4.5, 95% CI 2.0-9.9), symptom development (aOR=2.3, 95% CI 1.1-5.0), or interaction with primary case-patient (aOR=4.6, 95% CI 1.4-14.7) increased odds of case-household status. Households assessed for suitability for HBC reduced odds of case-household status (aOR=0.4, 95% CI=0.2-0.8). Interacting with a primary case-patient increased the risk of individual infection among household members (adjusted risk ratio=1.7, 95% CI 1.1-2.8).Conclusion:
Household and individual factors influence secondary infection risk in HBC. Decisions about HBC should be made with these in mind.
ABHR, Alcohol Based Hand Rub; AFENET, The African Field Epidemiology Network; CDC, Centers for Diseases Control and Prevention; COVID-19; COVID-19, Corono Virus Disease 2019; HBC, Home Based Care; HH, Household; MoH, Ministry of Health; PEPFAR, President's Emergency Plan for AIDS Relief; RT-PCR, Reverse Tanscription Polymerase Chain Reaction; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2; SES, Social Economic Status; Screening; TB, Tuberculosis; Uganda; home-based care (HBC); household contacts; pandemic
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Language:
English
Journal:
IJID Reg
Year:
2022
Document Type:
Article
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