Novelties in the evaluation of microcirculation in septic shock.
J Intensive Med
; 3(2): 124-130, 2023 Apr 30.
Article
in English
| MEDLINE | ID: covidwho-2105448
ABSTRACT
Microvascular alterations were first described in critically ill patients about 20 years ago. These alterations are characterized by a decrease in vascular density and presence of non-perfused capillaries close to well-perfused vessels. In addition, heterogeneity in microvascular perfusion is a key finding in sepsis. In this narrative review, we report our actual understanding of microvascular alterations, their role in the development of organ dysfunction, and the implications for outcome. Herein, we discuss the state of the potential therapeutic interventions and the potential impact of novel therapies. We also discuss how recent technologic development may affect the evaluation of microvascular perfusion.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
/
Prognostic study
/
Reviews
Language:
English
Journal:
J Intensive Med
Year:
2023
Document Type:
Article
Affiliation country:
J.jointm.2022.09.002
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