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Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022.
Atari, Nofar; Kliker, Limor; Zuckerman, Neta; Elkader, Bayan Abd; Weiss-Ottolenghi, Yael; Mendelson, Ella; Kreiss, Yitshak; Regev-Yochay, Gili; Mandelboim, Michal.
  • Atari N; Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
  • Kliker L; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Zuckerman N; Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
  • Elkader BA; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Weiss-Ottolenghi Y; Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
  • Mendelson E; Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
  • Kreiss Y; Sheba Medical Center, Tel-Hashomer, Israel.
  • Regev-Yochay G; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
  • Mandelboim M; Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Tel-Hashomer, Israel.
Euro Surveill ; 27(44)2022 11.
Article in English | MEDLINE | ID: covidwho-2109636
ABSTRACT
We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in vaccinated individuals resulted in increased neutralising antibodies against the WT and Omicron variants compared with vaccinated uninfected HCW. HCW who recovered from BA.1 or BA.5 infections showed similar neutralising antibodies levels against BA.2.75.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Topics: Vaccines / Variants Limits: Humans Country/Region as subject: Asia Language: English Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: 1560-7917.ES.2022.27.44.2200785

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Topics: Vaccines / Variants Limits: Humans Country/Region as subject: Asia Language: English Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: 1560-7917.ES.2022.27.44.2200785