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Electrochemical Gene Amplification Signal Detection of Disposable Biochips Using Electrodes.
Kim, Gyo-Rim; Hwang, Ji-Soo; Kim, Jong-Dae; Kim, Yu-Seop; Park, Chan-Young.
  • Kim GR; School of Software, Hallym University, Chuncheon-si 24252, Korea.
  • Hwang JS; Bio-IT Research Center, Hallym University, Chuncheon-si 24252, Korea.
  • Kim JD; School of Software, Hallym University, Chuncheon-si 24252, Korea.
  • Kim YS; Bio-IT Research Center, Hallym University, Chuncheon-si 24252, Korea.
  • Park CY; School of Software, Hallym University, Chuncheon-si 24252, Korea.
Sensors (Basel) ; 22(22)2022 Nov 09.
Article in English | MEDLINE | ID: covidwho-2110221
ABSTRACT
Real-time Polymerase Chain Reaction (RT-PCR), a molecular diagnostic technology, is spotlighted as one of the quickest and fastest diagnostic methods for the actual coronavirus (SARS-CoV-2). However, the fluorescent label-based technology of the RT-PCR technique requires expensive equipment and a sample pretreatment process for analysis. Therefore, this paper proposes a biochip based on Electrochemical Impedance Spectroscopy (EIS). In this paper, it was possible to see the change according to the concentration by measuring the impedance with a chip made of two electrodes with different shapes of sample DNA.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gene Amplification / COVID-19 Type of study: Diagnostic study Limits: Humans Language: English Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gene Amplification / COVID-19 Type of study: Diagnostic study Limits: Humans Language: English Year: 2022 Document Type: Article