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The drop in reported invasive pneumococcal disease among adults during the first COVID-19 wave in the Netherlands explained.
Dirkx, Kirsten K T; Mulder, Bert; Post, Annelies S; Rutten, Martijn H; Swanink, Caroline M A; Wertheim, Heiman F L; Cremers, Amelieke J H.
  • Dirkx KKT; Department of Clinical Microbiology and Infectious Diseases, Canisius-Wilhelmina Ziekenhuis, Nijmegen, the Netherlands; Department of Clinical Microbiology, Radboud Centre for Infectious Diseases, Radboudumc, Nijmegen, the Netherlands.
  • Mulder B; Department of Clinical Microbiology and Infectious Diseases, Canisius-Wilhelmina Ziekenhuis, Nijmegen, the Netherlands.
  • Post AS; Department of Clinical Microbiology and Infectious Diseases, Canisius-Wilhelmina Ziekenhuis, Nijmegen, the Netherlands.
  • Rutten MH; Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
  • Swanink CMA; Department of Clinical Microbiology and Immunology, Rijnstate, Arnhem, the Netherlands.
  • Wertheim HFL; Department of Clinical Microbiology, Radboud Centre for Infectious Diseases, Radboudumc, Nijmegen, the Netherlands.
  • Cremers AJH; Department of Clinical Microbiology, Radboud Centre for Infectious Diseases, Radboudumc, Nijmegen, the Netherlands.
Int J Infect Dis ; 111: 196-203, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-2113602
ABSTRACT

OBJECTIVES:

Streptococcus pneumoniae is the leading bacterial pathogen causing respiratory infections. Since the COVID-19 pandemic emerged, less invasive pneumococcal disease (IPD) was identified by surveillance systems worldwide. Measures to prevent transmission of SARS-CoV-2 also reduce transmission of pneumococci, but this would gradually lead to lower disease rates.

DESIGN:

Here, we explore additional factors contributing to the instant drop in pneumococcal disease cases captured in surveillance.

RESULTS:

Our observations on referral practices and other impediments to diagnostic testing indicate that residual IPD has likely occurred but remained undetected by conventional hospital-based surveillance.

CONCLUSIONS:

Depending on the setting, we discuss alternative monitoring strategies that could improve understanding of pneumococcal disease dynamics.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumococcal Infections / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Vaccines Limits: Adult / Humans / Infant Country/Region as subject: Europa Language: English Journal: Int J Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: J.ijid.2021.08.060

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumococcal Infections / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Vaccines Limits: Adult / Humans / Infant Country/Region as subject: Europa Language: English Journal: Int J Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: J.ijid.2021.08.060