factor V leiden mutation detection before astraZeneca vaccine
Italian Journal of Vascular and Endovascular Surgery
; 29(3):97-99, 2022.
Article
in English
| EMBASE | ID: covidwho-2114491
ABSTRACT
BacKgrouNd:
on the beginning of 2020 the world woke up with a novel coronavirus disease (coVId-19) pandemic caused by sarscoV-2, started in Wuhan, china. several types of vaccine appeared, one of them was astraZeneca (astraZenca, cambridge, uK) vaccine. METHOD(S) This is a single-center retrospective study which included 9 patients who developed DVT after the first dose of AstraZeneca vaccine. they were screened for thrombophilia, including factor V leiden mutation.rEsults:
they were found positive for factor V leiden mutation and were treated by Noacs. also, they were advised to delay second dose for 3 months and to shift to another vaccine like sinopharm (china National Pharmaceutical group, Beijing, china).coNclusIoNs:
alert should be raised for patients with factor V leiden mutation having a second dose;and for the treatment of the thrombosis condition. Copyright © 2022 EdIZIoNI MINErVa MEdIca.
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Vaccines
Language:
English
Journal:
Italian Journal of Vascular and Endovascular Surgery
Year:
2022
Document Type:
Article
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