Hematological Alterations in Patients Recovered from SARS-CoV-2 Infection in Havana, Cuba.
MEDICC Rev
; 24(2): 7-14, 2022 May 16.
Article
in English
| MEDLINE | ID: covidwho-2115047
ABSTRACT
INTRODUCTION:
COVID-19 sequelae, or the short-, medium-, and long-term manifestations of the disease are under continuous study. There are currently few reports on the evolution of hematological variables following a demonstrated absence of SARS-CoV-2 after infection.OBJECTIVE:
Identify hematological alterations in Cuban adults recovered from SARS-CoV-2 infection, and their relation with disease severity.METHODS:
We selected 348 persons recovered from COVID-19 residing in Havana, Cuba with an RT-PCR study negative for SARS-CoV-2 performed two weeks after hospital discharge; a structured survey was administered to obtain clinical-epidemiological data. Three groups were established according to COVID-19 clinical criteria asymptomatic, mild/moderately symptomatic, and severely symptomatic, which, in turn, were divided according to hospital discharge date and blood sample collection date. We performed hemograms with differential leukocyte counts and compared results among groups. We then measured the associations between hematological variables, personal medical history, and relevant lifestyle habits (smoking).RESULTS:
All hematological variables were within normal reference limits, although men from the group of severely ill patients had increased total leukocytes, neutrophils and lymphocytes, and decreased hemoglobin and eosinophils, which was also evident in those with a recovery time of 31-90 days.CONCLUSIONS:
The relation between hematological variables and degree of clinical severity offers evidence as to persistence of systemic alterations (possibly inflammatory) associated with viral infection. Their identification and characterization can facilitate personalized patient followup and rehabilitation.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Qualitative research
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Adult
/
Humans
/
Male
Country/Region as subject:
Caribbean
/
Cuba
Language:
English
Journal:
MEDICC Rev
Journal subject:
Public Health
Year:
2022
Document Type:
Article
Affiliation country:
MR2022.V24.N2.1
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