New Insights into Avian Infectious Bronchitis Virus in Colombia from Whole-Genome Analysis.
Viruses
; 14(11)2022 Nov 19.
Article
in English
| MEDLINE | ID: covidwho-2116191
ABSTRACT
Infectious Bronchitis (IB) is a respiratory disease caused by a highly variable Gammacoronavirus, which generates a negative impact on poultry health worldwide. GI-11 and GI-16 lineages have been identified in South America based on Infectious Bronchitis virus (IBV) partial S1 sequences. However, full genome sequence information is limited. In this study we report, for the first time, the whole-genome sequence of IBV from Colombia. Seven IBV isolates obtained during 2012 and 2013 from farms with respiratory disease compatible with IB were selected and the complete genome sequence was obtained by NGS. According to S1 sequence phylogenetic analysis, six isolates belong to lineage GI-1 and one to lineage GVI-1. When whole genome was analyzed, five isolates were related to the vaccine strain Ma5 2016 and two showed mosaic genomes. Results from complete S1 sequence analysis provides further support for the hypothesis that GVI-1, considered a geographically confined lineage in Asia, could have originated in Colombia. Complete genome information reported in this research allow a deeper understanding of the phylogenetic evolution of variants and the recombination events between strains that are circulating worldwide, contributing to the knowledge of coronavirus in Latin America and the world.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Poultry Diseases
/
Infectious bronchitis virus
Type of study:
Observational study
/
Randomized controlled trials
Topics:
Vaccines
/
Variants
Limits:
Animals
Country/Region as subject:
South America
/
Colombia
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
V14112562
Similar
MEDLINE
...
LILACS
LIS