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A time-delayed model for the spread of COVID-19 with vaccination.
Al-Tuwairqi, Salma M; Al-Harbi, Sara K.
  • Al-Tuwairqi SM; Mathematics Department, King Abdulaziz University, Jeddah, Saudi Arabia. saltuwairqi@kau.edu.sa.
  • Al-Harbi SK; Mathematics Department, King Abdulaziz University, Jeddah, Saudi Arabia.
Sci Rep ; 12(1): 19435, 2022 Nov 13.
Article in English | MEDLINE | ID: covidwho-2119152
ABSTRACT
A mathematical model is presented in this paper to investigate the effects of time delay in vaccine production on COVID-19 spread. The model is analyzed qualitatively and numerically. The qualitative analysis indicates that the system variables are non-negative, bounded, and biologically meaningful. Moreover, the model has produced two equilibrium points the free equilibrium point, which can exist without conditions, and the endemic equilibrium point, which can exist if the control reproduction number, [Formula see text], is not less than one. In addition, the local stability of the equilibrium points is investigated and agrees with the numerical analysis results. Finally, a sensitivity analysis is conducted for [Formula see text]. In particular, we examine the effect of the vaccine's time delay, vaccine rate, and vaccine efficiency on the model dynamics.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Qualitative research Topics: Vaccines Limits: Humans Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-23822-5

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Qualitative research Topics: Vaccines Limits: Humans Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-23822-5