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Antibodies as drugs-a Keystone Symposia report.
Cable, Jennifer; Saphire, Erica Ollmann; Hayday, Adrian C; Wiltshire, Timothy D; Mousa, Jarrod J; Humphreys, David P; Breij, Esther C W; Bruhns, Pierre; Broketa, Matteo; Furuya, Genta; Hauser, Blake M; Mahévas, Matthieu; Carfi, Andrea; Cantaert, Tineke; Kwong, Peter D; Tripathi, Prabhanshu; Davis, Jonathan H; Brewis, Neil; Keyt, Bruce A; Fennemann, Felix L; Dussupt, Vincent; Sivasubramanian, Arvind; Kim, Philip M; Rawi, Reda; Richardson, Eve; Leventhal, Daniel; Wolters, Rachael M; Geuijen, Cecile A W; Sleeman, Matthew A; Pengo, Niccolo; Donnellan, Francesca Rose.
  • Cable J; PhD Science Writer, New York, New York, USA.
  • Saphire EO; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, California, USA.
  • Hayday AC; Department of Medicine, University of California San Diego, La Jolla, California, USA.
  • Wiltshire TD; Peter Gorer Department of Immunobiology, King's College London, London, UK.
  • Mousa JJ; Cancer Research UK Cancer Immunotherapy Accelerator, London, UK.
  • Humphreys DP; Immunosurveillance Laboratory, The Francis Crick Institute, London, UK.
  • Breij ECW; Mayo Clinic, Rochester, Minnesota, USA.
  • Bruhns P; Department of Infectious Diseases and Center for Vaccines and Immunology, College of Veterinary Medicine, Athens, Georgia, USA.
  • Broketa M; Department of Biochemistry and Molecular Biology, Franklin College of Arts and Sciences, University of Georgia, Athens, Georgia, USA.
  • Furuya G; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Hauser BM; Protein Sciences, UCB Pharma, Berkshire, UK.
  • Mahévas M; Translational Research and Precision Medicine, Genmab BV, Utrecht, the Netherlands.
  • Carfi A; Institut Pasteur, Université de Paris, Unit of Antibodies in Therapy and Pathology, Paris, France.
  • Cantaert T; Institut Pasteur, Université de Paris, Unit of Antibodies in Therapy and Pathology, Paris, France.
  • Kwong PD; Department of Preventive Medicine and Department of Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Tripathi P; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.
  • Davis JH; Service de Médecine Interne, Centre de Référence des Cytopénies Auto-immunes de l'adulte, Centre Hospitalier Universitaire Henri-Mondor, Assistance Publique-Hôpitaux de Paris, Université Paris-Est Créteil, Créteil, France.
  • Brewis N; Moderna Inc., Cambridge, Massachusetts, USA.
  • Keyt BA; Department of Pathology, Miller School of Medicine, University of Miami, Miami, Florida, USA.
  • Fennemann FL; Immunology Unit, Institut Pasteur du Cambodge, The Pasteur Network, Phnom Penh, Cambodia.
  • Dussupt V; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Sivasubramanian A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Kim PM; Invenra, Inc, Madison, Wisconsin, USA.
  • Rawi R; F-star Therapeutics Ltd., Cambridge, UK.
  • Richardson E; IGM Biosciences, Inc., Mountainview, California, USA.
  • Leventhal D; Lava Therapeutics, Utrecht, the Netherlands.
  • Wolters RM; Emerging Infectious Diseases Branch, U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Geuijen CAW; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA.
  • Sleeman MA; Computational Biology, Adimab, Palo Alto, California, USA.
  • Pengo N; Department of Molecular Genetics, Donnelly Centre for Cellular and Biomolecular Research, Toronto, Ontario, Canada.
  • Donnellan FR; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.
Ann N Y Acad Sci ; 2022 Nov 16.
Article in English | MEDLINE | ID: covidwho-2237733
ABSTRACT
Therapeutic antibodies have broad indications across diverse disease states, such as oncology, autoimmune diseases, and infectious diseases. New research continues to identify antibodies with therapeutic potential as well as methods to improve upon endogenous antibodies and to design antibodies de novo. On April 27-30, 2022, experts in antibody research across academia and industry met for the Keystone symposium "Antibodies as Drugs" to present the state-of-the-art in antibody therapeutics, repertoires and deep learning, bispecific antibodies, and engineering.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2022 Document Type: Article Affiliation country: Nyas.14915

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Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2022 Document Type: Article Affiliation country: Nyas.14915