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The Significant Impact of Narcan Reversals on Overdose Mortality in Peoria County, IL.
Al-Tabbaa, Mohammad Mousbah; Bdiwi, Ehssan; Endress, Kathryn; Altarras, Khaled.
  • Al-Tabbaa MM; Internal Medicine, University of Illinois College of Medicine Peoria, Peoria, USA.
  • Bdiwi E; Internal Medicine, Kalamon University, Damascus, SYR.
  • Endress K; Public Health, Peoria City/County Health Department, Peoria, USA.
  • Altarras K; Dentistry, Damascus University, Faculty of Dentistry, Damascus, SYR.
Cureus ; 14(10): e29918, 2022 Oct.
Article in English | MEDLINE | ID: covidwho-2121001
ABSTRACT

OBJECTIVES:

Determine the impact of Narcan administrations in Peoria County, IL on the number of overdose deaths by testing the statistical significance of the association between monthly Narcan reversals and overdose mortality. As well as re-shedding the light on the opioid pandemic post-COVID.

METHODS:

We collected data on Narcan reversals from hospital emergency departments, Emergency Medical Services (EMS), the County Sheriff's Office, local police departments, and other agencies that distributed and/or administered Narcan in Peoria County from January through December 2018. Data for the 2018 overdose mortality was collected through vital records at the Peoria City/County Health Department.

RESULTS:

Results from simple linear regression suggest that a significant proportion of the total variation in overdose mortality over 2018 was predicted by the Narcan reversals, F(1, 11) = 5.872, p< 0.05. Multiple R2 indicates that approximately 30.7% of the variation in overdose mortality was predicted by the Narcan reversals. If there were 0 Narcan reversals, there would be 8.362 overdose deaths per month.

CONCLUSIONS:

Narcan is known to save lives in cases of opioid overdose, and the need for increased administration campaigns is warranted to further battle the opioid epidemic. As this study has proven, Narcan administration has the potential to significantly decrease overdose mortality.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study Topics: Long Covid Language: English Journal: Cureus Year: 2022 Document Type: Article Affiliation country: Cureus.29918

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study Topics: Long Covid Language: English Journal: Cureus Year: 2022 Document Type: Article Affiliation country: Cureus.29918