147th Annual Meeting American Neurological Association

ABSTRACT

The proceedings contain 417 papers. The topics discussed include APOE is independently associated with the heterogeneity of cognitive decline rate in the normal aging-early Alzheimer's disease continuum;bioequivalence and safety comparison of once-weekly donepezil transdermal system with once-daily oral donepezil results of a phase 1 trial in healthy volunteers;bleed type as a predictor of emotional and behavioral dyscontrol following intracerebral and subarachnoid hemorrhage;case series of manic symptoms following concussion;cognitive impairment in pulmonary hypertension;Creutzfeldt Jacob disease misdiagnosis, a diagnostic challenge and psychological burden a case series;depressed neurocognitive function with comprehensive neuropsychiatric evaluation among long-haul COVID patients;evaluation of skin adhesion and local skin tolerability of once-weekly donepezil transdermal system results of a phase 1 trial in healthy volunteers;determining etiologic diagnoses in rapidly progressive dementia a clinical study;and frequency and distribution of transactive response DNA-binding protein 43 (TDP-43) pathology across the age spectrum in an elderly cohort with and without dementia.