Antibody-mediated Rejection of Kidney Allografts Following COVID-19: A Report of Two Cases.
Iran J Kidney Dis
; 16(6): 330-336, 2022 Nov.
Article
in English
| MEDLINE | ID: covidwho-2124962
ABSTRACT
Increased risk of graft rejection could be the consequence of COVID-19 in kidney transplant recipients (KTRs). We report two cases of kidney transplant (KT) with stable graft function who experienced antibody-mediated rejection (ABMR) following recovery from COVID-19. It seems that reduced immunosuppression during the acute illness, is the main explanation for post-COVID-19 ABMR. However, the inflammatory state associated with COVID-19, as well as direct cytopathic effects of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can predispose the kidney allograft to rejection. There is no definite guideline for the modification of immunosuppressives during COVID-19 in kidney transplant recipients. However, re-institution of full-dose immunosuppressives soon after recovery from COVID-19 and frequent outpatient follow-up visits are recommended. DOI 10.52547/ijkd.7176.
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Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Case report
/
Cohort study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Iran J Kidney Dis
Journal subject:
Nephrology
Year:
2022
Document Type:
Article
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