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Two pediatric cases of multisystem inflammatory-like syndrome following COVID-19 vaccination.
Collignon, C; Frachette, C; Callot, D; Pinhas, Y; Bataille, P; Bader-Meunier, B; Chouchana, L; Frémond, M-L; Belhadjer, Z; Oualha, M; Moulin, F; Javouhey, E; Belot, A; Renolleau, S.
  • Collignon C; Pediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France. Electronic address: charlotte.collignon@aphp.fr.
  • Frachette C; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, 69677 Bron, France; Faculty of Medicine, University of Lyon, 69100 Villeurbanne, France; National Referee Centre for Rheumatic and Autoimmune and Systemic Diseases in Children (RAISE), 69677 Bro
  • Callot D; Regional Center of Pharmacovigilance, Department of Pharmacology, Cochin Hospital, AP-HP. Centre - Université de Paris, Paris, France.
  • Pinhas Y; Department of General Pediatrics and Pediatric Infectious Diseases, Necker-Enfants-Malades University Hospital, APHP, Centre-Université de Paris, Paris, France; Université de Paris, Paris, France.
  • Bataille P; Université de Paris, Paris, France; Department of Dermatology, Reference Centre for Genodermatoses and Rare Skin Disease (MAGEC), Hopital Universitaire Necker-Enfants Malades, APHP, Paris, France.
  • Bader-Meunier B; Université de Paris, Paris, France; Department of Pediatric Immunology and Rheumatology, AP-HP, Necker Hospital, Paris, France.
  • Chouchana L; Regional Center of Pharmacovigilance, Department of Pharmacology, Cochin Hospital, AP-HP. Centre - Université de Paris, Paris, France.
  • Frémond ML; Université de Paris, Paris, France; Department of Pediatric Immunology and Rheumatology, AP-HP, Necker Hospital, Paris, France.
  • Belhadjer Z; M3C-Necker Enfants Malades, AP-HP, Paris, France.
  • Oualha M; Pediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France; Université de Paris, Paris, France.
  • Moulin F; Pediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France.
  • Javouhey E; Faculty of Medicine, University of Lyon, 69100 Villeurbanne, France; Pediatric Intensive Care Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, 69677 Bron, France.
  • Belot A; National Referee Centre for Rheumatic and Autoimmune and Systemic Diseases in Children (RAISE), 69677 Bron, France; Lyon Immunopathology Federation LIFE, Hospices Civils de Lyon, 69002 Lyon, France; Pediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère Enfant, Hospices Civils de L
  • Renolleau S; Pediatric Intensive Care Unit, APHP University Hospital Necker-Enfants malades, Paris, France; Université de Paris, Paris, France.
Arch Pediatr ; 29(8): 620-623, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2130080
ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) is a novel post-infectious disease occurring in the context of SARS-CoV2 infection. COVID-19 vaccines have been authorized since December 2020, and adverse events including myocarditis have been reported following vaccination. We describe the cases of two pediatric patients presenting with clinical and laboratory features suggestive of MIS-C a few days after receiving their first dose of the Pfizer BNT162b2 vaccine. The outcome was favorable for both patients (after corticosteroid and immunoglobulin administration for one patient). These cases suggest an association between the COVID-19 vaccine and the occurrence of MIS-C.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Child / Humans Language: English Journal: Arch Pediatr Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Child / Humans Language: English Journal: Arch Pediatr Year: 2022 Document Type: Article