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COVID-19 and Cardiovascular Disease.
Clerkin, Kevin J; Fried, Justin A; Raikhelkar, Jayant; Sayer, Gabriel; Griffin, Jan M; Masoumi, Amirali; Jain, Sneha S; Burkhoff, Daniel; Kumaraiah, Deepa; Rabbani, LeRoy; Schwartz, Allan; Uriel, Nir.
  • Clerkin KJ; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Fried JA; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Raikhelkar J; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Sayer G; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Griffin JM; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Masoumi A; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Jain SS; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Burkhoff D; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Kumaraiah D; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Rabbani L; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Schwartz A; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
  • Uriel N; Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York.
Circulation ; 141(20): 1648-1655, 2020 May 19.
Article in English | MEDLINE | ID: covidwho-2138307
ABSTRACT
Coronavirus disease 2019 (COVID-19) is a global pandemic affecting 185 countries and >3 000 000 patients worldwide as of April 28, 2020. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2, which invades cells through the angiotensin-converting enzyme 2 receptor. Among patients with COVID-19, there is a high prevalence of cardiovascular disease, and >7% of patients experience myocardial injury from the infection (22% of critically ill patients). Although angiotensin-converting enzyme 2 serves as the portal for infection, the role of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers requires further investigation. COVID-19 poses a challenge for heart transplantation, affecting donor selection, immunosuppression, and posttransplant management. There are a number of promising therapies under active investigation to treat and prevent COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Cardiovascular Diseases / Coronavirus Infections / Peptidyl-Dipeptidase A / Pandemics / Betacoronavirus Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Journal: Circulation Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Cardiovascular Diseases / Coronavirus Infections / Peptidyl-Dipeptidase A / Pandemics / Betacoronavirus Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Journal: Circulation Year: 2020 Document Type: Article