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Jugular Paraganglioma Presenting with a Tumor Thrombus Extending from Posterior Fossa to Right Atrium and Multiple Skeletal Metastases.
Pehlivan, Umur Anil; Oktay, Kadir; Onan, Hasan Bilen; Acikalin, Arbil; Keser, Celalet; Paydas, Semra.
  • Pehlivan UA; Department of Radiology, Van Baskale State Hospital, Van, Turkey.
  • Oktay K; Department of Neurosurgery, Çukurova University School of Medicine, Adana, Turkey.
  • Onan HB; Department of Radiology, Çukurova University School of Medicine, Adana, Turkey.
  • Acikalin A; Department of Pathology, Çukurova University School of Medicine, Adana, Turkey.
  • Keser C; Department of Anaesthesiology, Çukurova University School of Medicine, Adana, Turkey.
  • Paydas S; Department of Medical Oncology, Çukurova University School of Medicine, Adana, Turkey.
Curr Med Imaging ; 18(13): 1439-1442, 2022.
Article in English | MEDLINE | ID: covidwho-2141254
ABSTRACT

INTRODUCTION:

Paragangliomas are tumors of neuroendocrine origin, may appear in different localizations, and are related to the autonomic nervous system. Paragangliomas are generally asymptomatic and may rarely appear with adrenergic symptoms, and clinical findings depend on the catecholamines they secrete. Extra-adrenal paragangliomas are mostly benign, like all paragangliomas. Malignancy criteria consist of local recurrence, metastasis after total resection, and presence of distant metastasis during primary diagnosis. CASE PRESENTATION This report presents the case of a 31-year-old man with jugular paraganglioma, multiple skeletal metastases, and a long-segment tumor thrombus. Imaging procedures showed a continuous tumor thrombus extending from the posterior fossa to the right atrium and metastases in C2, T1, T6, T8, L5, and right humerus. Histopathological assessment of the metastasis in C2 identified malignant paraganglioma. Curative surgery was not an option for this patient, hence combined chemotherapy was given.

CONCLUSION:

In cases of malignant paraganglioma with multiple distant metastases, chemotherapy and radiotherapy are feasible treatment methods.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Paraganglioma / Thrombosis Type of study: Case report / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Language: English Journal: Curr Med Imaging Year: 2022 Document Type: Article Affiliation country: 1573405618666220602121607

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Paraganglioma / Thrombosis Type of study: Case report / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Language: English Journal: Curr Med Imaging Year: 2022 Document Type: Article Affiliation country: 1573405618666220602121607