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Comprehensive update on the monkeypox outbreak.
Karim, Asad Mustafa; Kwon, Jeong Eun; Karim, Mujahid Aizaz; Iftikhar, Haseeb; Yasir, Muhammad; Ullah, Irfan; Kang, Se Chan.
  • Karim AM; Department of Oriental Medicine Biotechnology, College of Life Science, Kyung Hee University, Yongin, Gyeonggi, South Korea.
  • Kwon JE; Department of Oriental Medicine Biotechnology, College of Life Science, Kyung Hee University, Yongin, Gyeonggi, South Korea.
  • Karim MA; Sheikh Zayed Hospital and Medical College, Rahim Yar Khan, Punjab, Pakistan.
  • Iftikhar H; Sheikh Zayed Hospital and Medical College, Rahim Yar Khan, Punjab, Pakistan.
  • Yasir M; Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Ullah I; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Kang SC; Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States.
Front Microbiol ; 13: 1037583, 2022.
Article in English | MEDLINE | ID: covidwho-2324006
ABSTRACT
Monkeypox (MPX) was first reported in 1970 in humans and outbreaks were restricted and highly localised to endemic regions of western and central Africa. However, after the first reported case in the UK in early May, 2022, the pattern of epidemic spreading in the geographical regions was much larger compared to past, posing a risk MPX might become entrenched beyond endemic areas. This virus is less transmissible than SARS-CoV-2, as it transmitted mainly through personal, close, often skin-to-skin contact with infectious MPX rash, body fluids, or scabs from an individual with MPX. Infections usually present with chills, fever, fatigue, muscle aches, headache, sore throat, skin lesions, and lymphadenopathy. Currently, there are no antivirals approved for MPX. However, an antiviral drug called "tecovirimat," approved for the treatment of smallpox, has been made accessible to treat MPX. Moreover, to prevent MPX, there are two vaccines available which are approved by FDA Bavarian Nordic JYNNEOS, and ACAM2000 vaccine. Contact tracing is absent in case of MPX outbreak and there is lack of information from the data systems in rapid manner. Additionally, test capacity needs to be increased. Like SARS-CoV-2, global MPX outbreak demand for vaccines far exceeds availability.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines Language: English Journal: Front Microbiol Year: 2022 Document Type: Article Affiliation country: Fmicb.2022.1037583

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines Language: English Journal: Front Microbiol Year: 2022 Document Type: Article Affiliation country: Fmicb.2022.1037583