Different Clinical Uses and Advantages of Melatonin

ABSTRACT

Introduction: Melatonin (N-acetyl-5-methoxytryptamine), an endogenous hormone produced by the pineal gland and released exclusively at night, is known to influence many biological processes in the body, including circadian rhythms, the immune system, and neuroendocrine and cardiovascular functions, due to its great therapeutic potential and safety for application. This molecule is being widely studied in order to establish safe and effective therapeutic protocols for the treatment of several disorders, such as sleep disorders, cardiovascular diseases, metabolic bone diseases, covid-19, schizophrenia, neurofetal protection, among others. In view of this, the present article aims to demonstrate the numerous possible applications and their respective benefits of melatonin use. © 2022 Thieme Medical Publishers, Inc.. All rights reserved.