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Innatus immunis: Evolving paradigm of adaptive NK cells.
Khalil, Mohamed; Malarkannan, Subramaniam.
  • Khalil M; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI.
  • Malarkannan S; Blood Research Institute, Versiti, Milwaukee, WI.
J Exp Med ; 219(11)2022 11 07.
Article in English | MEDLINE | ID: covidwho-2151771
ABSTRACT
The mechanisms that govern the development of adaptive-like NK cells are elusive. Shemesh et al. (2022. J. Exp. Med.https//doi.org/10.1084/jem.20220551) report that the development of FcRγ-/low adaptive-like NK cells requires reduced mTOR activity and depends on TGF-ß or IFN-α. These findings provide exciting new molecular blueprints explaining the development and functions of adaptive-like NK cells.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Killer Cells, Natural / Transforming Growth Factor beta Language: English Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Killer Cells, Natural / Transforming Growth Factor beta Language: English Year: 2022 Document Type: Article