Innatus immunis: Evolving paradigm of adaptive NK cells.
J Exp Med
; 219(11)2022 11 07.
Article
in English
| MEDLINE | ID: covidwho-2151771
ABSTRACT
The mechanisms that govern the development of adaptive-like NK cells are elusive. Shemesh et al. (2022. J. Exp. Med.https//doi.org/10.1084/jem.20220551) report that the development of FcRγ-/low adaptive-like NK cells requires reduced mTOR activity and depends on TGF-ß or IFN-α. These findings provide exciting new molecular blueprints explaining the development and functions of adaptive-like NK cells.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Killer Cells, Natural
/
Transforming Growth Factor beta
Language:
English
Year:
2022
Document Type:
Article
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