In Vivo, in Vitro Evaluation of the Effect of Mixed Plant Extract Used in the Prevention of the Reproduction & Transmission of Corona Virus inside Cells

ABSTRACT

It has become vital to look for innovative antiviral medications from plants and other natural sources as alternatives for prophylaxis during the novel coronavirus disease 2019 (COVID-19) pandemic. The antiviral potential of mixed extract (artemisinin and linen seed) is reviewed in this study for the treatment and prophylaxis of coronavirus disease. Based on their origin, native area, utilized plant parts, and antiviral potentials, therapeutic herbs and crops have been described in detail. It has been detailed how plant-derived natural antiviral chemicals may play a part in the development of plant-based coronavirus medications. Objective(s) This study highlights the effect of the mixed extract (artemisinin and linen seed) as potential preventative agents and therapeutic treatments for SARS-CoV-2 at early stages of infection. Material(s) and Method(s) 18 mice was selected in this study & divided into 3 group Group A Containing 6 mice were only fed without any medication or virus administrated to be a control group. Group B Containing 6 mice injected by COVID-19 without the administration of the treatment. Group C Containing 6 mice injected by COVID-19 and after 5 days of injection, the extract was administrated. Result(s) we can concluded that the mixture prevent the virus to inter the cell without any effect on the human cell especially if we know the human body can remove all the part of mixture within one to two days. Conclusion(s) The active ingredient(s) in the extracts from A. annua are probably other than artemisinin or a mixture of ingredients that impede viral infection at a stage downstream of viral entry. Additional research will look at in vivo activity to see if A. annua can cure SARS-CoV-2 infections at a reasonable price. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.