A Highly Sensitive Graphene-based Field Effect Transistor for the Detection of Myoglobin
Silicon
; 14(17):11741-11748, 2022.
Article
in English
| ProQuest Central | ID: covidwho-2158188
ABSTRACT
Biomedical applications adapt Nano technology-based transistors as a key component in the biosensors for diagnosing life threatening diseases like Covid-19, Acute myocardial infarction (AMI), etc. The proposed work introduces a new biosensor, based on Graphene Field Effect Transistor (GFET), which is used in the diagnosis of Myoglobin (Mb) in human blood. Graphene-based biosensors are faster, more precise, stronger, and more trustworthy. A GFET is created in this study for the detection of myoglobin biomarker at various low concentrations. Because graphene is sensitive to a variety of biomarker materials, it can be employed as a gate material. When constructed Graphene FET is applied to myoglobin antigens, it has a significant response. The detection level for myoglobin is roughly 30 fg/ml, which is quite high. The electrical behavior of the GFET-based biosensor in detecting myoglobin marker is ideal for Lab-on-Chip platforms and Cardiac Point-of-Care Diagnosis.
Full text:
Available
Collection:
Databases of international organizations
Database:
ProQuest Central
Type of study:
Diagnostic study
/
Experimental Studies
Language:
English
Journal:
Silicon
Year:
2022
Document Type:
Article
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