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COVID-19: Postmortem Diagnostic and Biosafety Considerations.
Am J Forensic Med Pathol ; 41(3): 143-151, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-215983
ABSTRACT
As a result of the 2019 novel human coronavirus (COVID-19) global spread, medical examiner/coroner offices will inevitably encounter increased numbers of COVID-19-infected decedents at autopsy. While in some cases a history of fever and/or respiratory distress (eg, cough or shortness of breath) may suggest the diagnosis, epidemiologic studies indicate that the majority of individuals infected with COVID-19 develop mild to no symptoms. Those dying with-but not of-COVID-19 may still be infectious, however. While multiple guidelines have been issued regarding autopsy protocol in cases of suspected COVID-19 deaths, there is some variability in the recommendations. Additionally, limited recommendations to date have been issued regarding scene investigative protocol, and there is a paucity of publications characterizing COVID-19 postmortem gross and histologic findings. A case of sudden unexpected death due to COVID-19 is presented as a means of illustrating common autopsy findings, as well as diagnostic and biosafety considerations. We also review and summarize the current COVID-19 literature in an effort to provide practical evidence-based biosafety guidance for medical examiner-coroner offices encountering COVID-19 at autopsy.
Subject(s)
Full text: Available Collection: International databases Database: MEDLINE Type: Article Main subject: Pneumonia, Viral / Autopsy / Coronavirus Infections / Containment of Biohazards / Betacoronavirus Subject: Pneumonia, Viral / Autopsy / Coronavirus Infections / Containment of Biohazards / Betacoronavirus Type of study: Case report / Diagnostic study Language: English Journal: Am J Forensic Med Pathol Year: 2020

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Full text: Available Collection: International databases Database: MEDLINE Type: Article Main subject: Pneumonia, Viral / Autopsy / Coronavirus Infections / Containment of Biohazards / Betacoronavirus Subject: Pneumonia, Viral / Autopsy / Coronavirus Infections / Containment of Biohazards / Betacoronavirus Type of study: Case report / Diagnostic study Language: English Journal: Am J Forensic Med Pathol Year: 2020