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Type 2 diabetes.
Ahmad, Ehtasham; Lim, Soo; Lamptey, Roberta; Webb, David R; Davies, Melanie J.
  • Ahmad E; Diabetes Research Centre, University of Leicester and the Leicester NIHR Biomedical Research Centre, Leicester General Hospital, Leicester, UK.
  • Lim S; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
  • Lamptey R; Family Medicine Department, Korle Bu Teaching Hospital, Accra Ghana and Community Health Department, University of Ghana Medical School, Accra, Ghana.
  • Webb DR; Diabetes Research Centre, University of Leicester and the Leicester NIHR Biomedical Research Centre, Leicester General Hospital, Leicester, UK.
  • Davies MJ; Diabetes Research Centre, University of Leicester and the Leicester NIHR Biomedical Research Centre, Leicester General Hospital, Leicester, UK. Electronic address: melanie.davies@uhl-tr.nhs.uk.
Lancet ; 400(10365): 1803-1820, 2022 11 19.
Article in English | MEDLINE | ID: covidwho-2159959
ABSTRACT
Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes worldwide. The number affected is increasing rapidly with alarming trends in children and young adults (up to age 40 years). Early detection and proactive management are crucial for prevention and mitigation of microvascular and macrovascular complications and mortality burden. Access to novel therapies improves person-centred outcomes beyond glycaemic control. Precision medicine, including multiomics and pharmacogenomics, hold promise to enhance understanding of disease heterogeneity, leading to targeted therapies. Technology might improve outcomes, but its potential is yet to be realised. Despite advances, substantial barriers to changing the course of the epidemic remain. This Seminar offers a clinically focused review of the recent developments in type 2 diabetes care including controversies and future directions.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Epidemics Type of study: Observational study / Prognostic study Limits: Adult / Child / Humans / Young adult Language: English Journal: Lancet Year: 2022 Document Type: Article Affiliation country: S0140-6736(22)01655-5

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Epidemics Type of study: Observational study / Prognostic study Limits: Adult / Child / Humans / Young adult Language: English Journal: Lancet Year: 2022 Document Type: Article Affiliation country: S0140-6736(22)01655-5