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Clinical Profile of COVID-19 Positive Neonates in a Tertiary Care Hospital
Journal of Neonatology ; 36(4):298-301, 2022.
Article in English | EMBASE | ID: covidwho-2162195
ABSTRACT

Objective:

To evaluate clinical profiles of COVID-19 neonates and compare early onset (<7 days) vs late onset (>=7 days) COVID. Method(s) Prospective observational study conducted among the neonates who were at risk or COVID-19 positive and who were admitted consecutively in one year (from June 2020 to May 2021) to evaluate their clinical status. At risk neonates underwent RT-PCR for oropharyngeal swab within 24 to 48 hours of life (inborn) or after admission (outborn). Result(s) Out of 351 at risk neonates, 106 babies came positive (early = 35.4% and late = 64.6%). Twelve (11.3%) cases were positive within 24 to 48 hours of life, indicating perinatal transmission. A total of 62 (58.4%) positive newborns were symptomatic. In their clinical course, there was Respiratory distress in 33(31.1%), diarrhoea in 7 (6.6%), poor feeding or lethargy in 24 (23.1%), fever in 19 (17.9 %) neonates. One baby developed COVID MIS-N. Early onset group was more symptomatic (P value <.05) but late onset group had a longer hospital stay (Spearman's rho <0.5) and increased duration of oxygen requirement (t-test sig. [2-tailed] < 0.05). Conclusion(s) There is high incidence of perinatal transmission. Early onset group was more symptomatic but late onset group had increased duration of oxygen requirement and longer hospital stay. Copyright © 2022 National Neonatology Forum.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: English Journal: Journal of Neonatology Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Prognostic study Language: English Journal: Journal of Neonatology Year: 2022 Document Type: Article