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The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation.
Liu, Wendao; Ye, Xiaohua; An, Zhiqiang; Zhao, Zhongming.
  • Liu W; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St. Suite 600, Houston, TX, 77030, USA.
  • Ye X; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA.
  • An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Zhao Z; MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA.
Virol J ; 19(1): 217, 2022 12 15.
Article in English | MEDLINE | ID: covidwho-2162390
ABSTRACT
The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequencing to accelerate both basic research and therapeutic development for COVID-19 and other emerging infectious diseases.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Virol J Journal subject: Virology Year: 2022 Document Type: Article Affiliation country: S12985-022-01923-x

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Virol J Journal subject: Virology Year: 2022 Document Type: Article Affiliation country: S12985-022-01923-x