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COVID-19 Still Surprising Us-A Rare Movement Disorder Induced by Infection.
Sirbu, Carmen Adella; Popescu, Diana; Stefan, Ion; Stefani, Constantin; Mitrica, Marian; Anghel, Daniela.
  • Sirbu CA; Department of Neurology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
  • Popescu D; Department of Neurology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
  • Stefan I; Department of Medico-Surgical and Prophylactic Disciplines, Titu Maiorescu University, 031593 Bucharest, Romania.
  • Stefani C; Department of Infectious Diseases, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
  • Mitrica M; Department No. 5, University of Medicine and Pharmacy "Carol Davila", 050474 Bucharest, Romania.
  • Anghel D; Clinical Neurosciences Department, University of Medicine and Pharmacy "Carol Davila" Bucharest, 050474 Bucharest, Romania.
Brain Sci ; 12(12)2022 Dec 17.
Article in English | MEDLINE | ID: covidwho-2163245
ABSTRACT

BACKGROUND:

Many neurological manifestations are part of COVID-19 infections, including movement disorders, but a clinical picture closely resembling stiff-person syndrome has not yet been described. CASE PRESENTATION We report a case of a stiff-person-like syndrome in the context of COVID-19 infection. A 79-year-old woman, with no prior history of diseases, presented global reversible stiffness associated with SARS-CoV-2 infection. We aim to shed light on several particularities regarding this clinical picture and its evolution in close relationship with the infectious disease progression, with full regression of symptoms and signs once the infectious process ceased. The impairment of speech and motility caused the wrong diagnosis of stroke in the Emergency Room. In addition, we would also like to emphasize the concomitant rhabdomyolysis, closely linked to the grade of muscle rigidity.

CONCLUSIONS:

We would like to raise awareness regarding this clinical setting and its association with SARS-COV-2 infection, to aid in its future recognition and management. To our knowledge, this is the first case of a stiff-person-like syndrome to be described in association with COVID-19 infection.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: Brainsci12121733

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: Brainsci12121733