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Profiling Cognitive Impairment in Mild COVID-19 Patients: A Case-Control Study at a Secondary Healthcare Centre in the Hilly Region of North India.
Khanna, Sanat Kumar; Khanna, Neelu; Malav, Manoj Kumar; Bayad, Himanshu Chhagan; Sood, Akshay; Abraham, Leena.
  • Khanna SK; Department of Surgery, Military Hospital Shimla, Shimla, Himachal Pradesh, India.
  • Khanna N; Department of Medicine, Shimla, Himachal Pradesh, India.
  • Malav MK; Department of Neurology, SN Medical College, Agra, Uttar Pradesh, India.
  • Bayad HC; Department of Otorhinolaryngology (ENT), Military Hospital Shimla, Shimla, Himachal Pradesh, India.
  • Sood A; Department of Emergency Medicine, Military Hospital Shimla, Shimla, Himachal Pradesh, India.
  • Abraham L; Department of Medicine, Military Hospital Shimla, Shimla, Himachal Pradesh, India.
Ann Indian Acad Neurol ; 25(6): 1099-1103, 2022.
Article in English | MEDLINE | ID: covidwho-2163881
ABSTRACT
Context COVID-19 pandemic continues to be a serious threat to humanity even after the last 2.5 years and multiple reported waves. Post-COVID-19 cognitive impairment has a detrimental effect on the quality of life, education, occupation, psychosocial as well as adaptive functioning and independence. Aims and

Objective:

Profiling the cognitive impairment in the mild COVID-19 recovered patients. Settings and

Design:

Interview-based case-control study. Materials and

Methods:

This study was conducted at a secondary healthcare center in a hilly region of north India. Group A included mild COVID-19 recovered patients and Group B included local non-COVID healthy individuals. Both groups of participants were interviewed using Montreal Cognitive Assessment (MoCA) to identify global and domain-wise cognitive impairment. Statistics Used Descriptive statistics were used to analyze the demographic and clinical variables. The Chi-square test was used to evaluate these results and statistical analysis was done using the Statistical Package for Social Sciences (version 23) program.

Results:

A total of 284 individuals were enrolled in our study, equally split into Groups A (cases) and B (controls). No global cognitive decline was found in any participant. However, 40 cases scored low on MoCA. The decrease in domain-wise cognitive function was statistically significant for visuospatial skill/executive function and attention.

Conclusion:

Our results have demonstrated that there is domain-wise cognitive impairment associated with mild COVID-19 disease. We recommend lowering the threshold of the MoCA to identify the early cognitive impairment and the inclusion of detailed cognitive assessment in post-COVID-19 follow-ups to initiate early cognitive rehabilitation among these patients.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Language: English Journal: Ann Indian Acad Neurol Year: 2022 Document Type: Article Affiliation country: Aian.aian_543_22

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Language: English Journal: Ann Indian Acad Neurol Year: 2022 Document Type: Article Affiliation country: Aian.aian_543_22