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Causes of Fever of unknown origin (FUO) in infants and children attending Assiut University Children's Hospital (AUCH)
Egyptian Journal of Hospital Medicine ; 89(2):7226-7230, 2022.
Article in English | Scopus | ID: covidwho-2164473
ABSTRACT

Background:

Fever of unknown origin (FUO) continues to be a diagnostic dilemma for pediatricians because it is often difficult to distinguish clinically between benign and potentially life-threatening causes. The term is best reserved for children with persistent fever >38 ˚c for which a cause could not be identified for more than 1 week. Aim of work to evaluate a four-stage investigative guideline for the detection of the causes of FUO among children.

Methods:

70 children aged between 6weeeks to 15 years with FUO were enrolled for this study. Graded investigations were done ranging from routine to advanced and/or specific investigations were performed after revision of detailed history and thorough examination.

Results:

outpatient investigations were done in 8.6% of the cases. The duration of FUO in this study ranged from 12 days to 8 weeks. The causes of FUO were 31.4% bacterial infection and 11.4% viral infection including Covid-19 infection in 7.1% of them, herpes simplex, and glandular fever in 3.4% of them.ENT affection was present in 4.3%, and the cardiac cause was found in 4.3% of the cases. Malignancy was encountered in 10% of the cases. In 21.4% of the cases, the cause of FUO was not diagnosed. In 10% of the cases, connective tissue disease was detected, and auto-inflammatory disease was encountered in 7.1% of the cases.

Conclusion:

not all cases of FUO should be admitted to a hospital, as some of them can be diagnosed and treated on an outpatient basis,. © 2022, Ain Shams University Faculty of Medicine. All rights reserved.
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Full text: Available Collection: Databases of international organizations Database: Scopus Language: English Journal: Egyptian Journal of Hospital Medicine Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Language: English Journal: Egyptian Journal of Hospital Medicine Year: 2022 Document Type: Article