Risk of SARS-CoV-2 infection in healthcare workers with inflammatory bowel disease: a case-control study.
Infect Prev Pract
; 5(1): 100267, 2023 Mar.
Article
in English
| MEDLINE | ID: covidwho-2165417
ABSTRACT
Background:
Whether healthcare workers with inflammatory bowel disease (IBD) are at increased risk of Novel coronavirus disease (COVID-19) due to occupational exposure is unknown.Aim:
To assess the risk of COVID-19 in healthcare workers with IBD.Methods:
A case control study enrolled 326 healthcare workers with IBD from 17 GETAID centres and matched non-healthcare workers with IBD controls (11) for gender, age, disease subtype and year of diagnosis. The study period was year 2020 during the COVID-19 outbreak.Results:
In total, 59 COVID-19 were recorded among cases (n = 32) and controls (n = 27), including 2 severe COVID-19 (requiring hospitalization, mechanic ventilation) but no death. No difference was observed between healthcare workers and controls regarding the overall incidence rates of COVID-19 4.9 ± 2.2 vs. 3.8 ± 1.9 per 100 patient-semesters, P = 0.34) and the overall incidence rates of severe COVID-19 (0.6 ± 7.8 vs. 0.3 ± 5.5 per 100 patient-semesters, P = 0.42). In multivariate analysis in the entire study population, COVID-19 was associated with patients with body mass index > 30 kg/m2 (HR = 2.48, 95%CI [1.13-5.44], P = 0.02).Conclusion:
Healthcare workers with IBD do not have an increased risk of COVID-19 compared with other patients with IBD.
COVID-19, Novel coronavirus disease; CRP, C-reactive protein; Crohn's disease; Healthcare worker; IBD, inflammatory bowel disease; Inflammatory bowel disease; SARS-CoV-2; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TNF, tumor necrosis factor-alpha; UC, ulcerative colitis; Ulcerative colitis
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Infect Prev Pract
Year:
2023
Document Type:
Article
Affiliation country:
J.infpip.2022.100267
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