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Prevalence and risk factors of depression and anxiety among Chinese adults who received SARS-CoV-2 vaccine - A cross-sectional survey.
Zhang, Xiaobo; Cai, Yang; Zhu, Kai; Liu, Zhenghao; Zhou, Quan; Zhu, Yingying; Zhou, Chaojun; Zhong, Zhenzhen; Liu, Yan; Xiao, Wei.
  • Zhang X; First People's Hospital of Changde City, 818 Renmin Road, 415000 Changde City, Hunan Province, China.
  • Cai Y; First People's Hospital of Changde City, 818 Renmin Road, 415000 Changde City, Hunan Province, China.
  • Zhu K; Jishou University, 120 Renmin South Road, 416000 Jishou City, Hunan Province, China.
  • Liu Z; First People's Hospital of Changde City, 818 Renmin Road, 415000 Changde City, Hunan Province, China.
  • Zhou Q; First People's Hospital of Changde City, 818 Renmin Road, 415000 Changde City, Hunan Province, China.
  • Zhu Y; Huashan Hospital, Shanghai Medical College, Fudan University, 12 Urumqi Middle Road, 200040 Shanghai, China.
  • Zhou C; First People's Hospital of Changde City, 818 Renmin Road, 415000 Changde City, Hunan Province, China.
  • Zhong Z; Jishou University, 120 Renmin South Road, 416000 Jishou City, Hunan Province, China.
  • Liu Y; First People's Hospital of Changde City, 818 Renmin Road, 415000 Changde City, Hunan Province, China. Electronic address: 252542162@qq.com.
  • Xiao W; First People's Hospital of Changde City, 818 Renmin Road, 415000 Changde City, Hunan Province, China. Electronic address: xiaowei1888888@163.com.
J Affect Disord ; 324: 53-60, 2023 03 01.
Article in English | MEDLINE | ID: covidwho-2165446
ABSTRACT

BACKGROUND:

Direct data reflecting the psychological problems during the nationwide SARS-CoV-2 vaccination campaign are scarce in China. The aim of this study was to assess the prevalence of depression and anxiety and investigate the associated risk factors after vaccination against SARS-CoV-2 among Chinese adults.

METHODS:

We conducted a web-based cross-sectional survey from June to July 2021. A structured questionnaire including the Patient Health Questionnaire-9(PHQ-9) and Generalized Anxiety Disorder-7(GAD-7) was used to investigated depression and anxiety symptoms. After excluding 223 ineligible records, a total of 6984 participants were included in our final analysis. Multivariable logistic regression analysis was used to examined the potential factors associated with depression or anxiety.

RESULTS:

Our data indicated that the overall prevalence of depression and anxiety was assessed at 19.39 % and 9.74 %, respectively. Participants who had vaccinated the second dose were more likely to have depressive symptoms (20.95 % vs.16.40 %) and anxiety symptoms (10.38 % vs. 8.51 %) than who had vaccinated the first dose. Multivariable logistic regression analysis indicated female gender, being healthcare worker, college or above and planning a pregnancy were all independently linked to depression or anxiety.

LIMITATIONS:

The present study was based on an online survey.

CONCLUSION:

The present study confirmed the presence of depression and anxiety among Chinese adults who received SARS-COV-2 vaccine, as well as the potential influencing factors. Additional attention and psychological support should be directed at these high-risk groups during SARS-CoV-2 vaccination campaign.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Vaccines Limits: Adult / Female / Humans / Pregnancy Country/Region as subject: Asia Language: English Journal: J Affect Disord Year: 2023 Document Type: Article Affiliation country: J.jad.2022.12.077

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Vaccines Limits: Adult / Female / Humans / Pregnancy Country/Region as subject: Asia Language: English Journal: J Affect Disord Year: 2023 Document Type: Article Affiliation country: J.jad.2022.12.077