Combined nasal- and oropharyngeal self-swab provides equivalent performance compared to professionally collected oropharyngeal swabs in detecting SARS-CoV-2 in a real-life setting.
J Virol Methods
; 313: 114667, 2023 03.
Article
in English
| MEDLINE | ID: covidwho-2165658
ABSTRACT
PURPOSE:
To investigate the performance of a combined nasal midturbinate- and oropharyngeal (NAOP) self-swab compared to a deep oropharyngeal (OP) swab by health care workers (HCW) in detecting SARS-CoV-2 in a real-life setting.METHODS:
Paired swabs from 1119 participants were included. RT-PCR were used to detect SARS-CoV-2 in both swab samples.RESULTS:
330 participants tested positive. The sensitivity of the combined self-swab and OP swab was 96.9 % and 95.4 % respectively, whereas the Ct-values for self-swabs were significantly lower compared to OP swabs.CONCLUSION:
The combined NAOP self-swab outperformed the OP swab and thus, the NAOP self-swab may be an alternative sampling method under the given circumstances.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
J Virol Methods
Year:
2023
Document Type:
Article
Affiliation country:
J.jviromet.2022.114667
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