Metal oxide nanocomposite-based electrochemical biosensing studies

ABSTRACT

The growing world population is facing challenges like energy crisis, environmental sustainability, global public health problems, etc. Among these, the resolution of public health issue is of prime importance for the people to live happily and enjoy each moment of their life. However, various diseases such as diabetes mellitus, HIV, cancer, Alzheimer's disease, stroke, and other neurological diseases have no permanent cure yet. New life-threatening diseases and viruses like COVID-19, Zika, Ebola, SARS, MERS and H1N1 etc. are affecting humans, which lead to loss of life. through Early diagnosis, proper medical treatment and accessible health monitoring systems can be both life saving and cost saving for the patients. Particularly, biosensing protocols in connection to early diagnosis as well as health monitoring have placed a significant importance in biomedical sector. In the current context where population and bio-testing capacity have a remarkable gap, the effect of prompt and specific detection of target molecules is also important from the point of view of biosensor field. Hence, the development of biomedical sensors having the features such as easy to handle, cost effective, short time span for analysis, multianalyte sensing, sophisticated digital display, etc. are the need of hour. For example, glucometer is a well-known example of biosensor device;glucometer measures the sugar content present in blood sample. Similarly, various sensors such as glucowatch, tooth enamel biosensor, colorimetric sweat biosensor, etc. have wide application in biosensing for the analysis of different biomolecules. © 2022 Elsevier Inc. All rights reserved.