Long follow-up of symptomatic Multiple Myeloma patients after Covid-19 vaccination (BNT162b2): A single-institution retrospective experience.
Leuk Res Rep
; 18: 100342, 2022.
Article
in English
| MEDLINE | ID: covidwho-2181342
ABSTRACT
Myeloma patients are at an increased risk of severe forms of Covid-19. We examined response to mRNA vaccine between myeloma patients (n.127) and healthy volunteers (n.50). Anti-spike IgG antibody were detected in 76.9% of evaluable patients. 23.1% of MM patients failed to respond at two doses of COVID-19 mRNA vaccine. Univariate analyses identified three independent adverse predictive factors of absence of immunological response to COVID-19 vaccine extreme plasmacytosis (p < 0.001), B2M (p 0.006), and haemoglobin (p 0.008). Multivariate analysis confirmed the extreme plasmacytosis and haemoglobin value as statistically significant variables.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Topics:
Long Covid
/
Vaccines
Language:
English
Journal:
Leuk Res Rep
Year:
2022
Document Type:
Article
Affiliation country:
J.lrr.2022.100342
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