Phytomedicines explored under in vitro and in silico studies against coronavirus: An opportunity to develop traditional medicines.
S Afr J Bot
; 2022 May 02.
Article
in English
| MEDLINE | ID: covidwho-2183022
ABSTRACT
The widespread COVID-19 pandemic, caused by novel coronavirus SARS-CoV-2, has emanated as one of the most life-threatening transmissible diseases. Currently, the repurposed drugs such as remdesivir, azithromycine, chloroquine, and hydroxychloroquine are being employed in the management of COVID-19 but their adverse effects are a matter of concern. In this regard, alternative treatment options i.e., traditional medicine, medicinal plants, and their phytochemicals, which exhibit significant therapeutic efficacy and show a low toxicity profile, are being explored. The current review aims at unraveling the promising medicinal plants, phytochemicals, and traditional medicines against SARS-CoV-2 to discover phytomedicines for the management of COVID-19 on the basis of their potent antiviral activities against coronaviruses, as demonstrated in various biochemical and computational chemical biology studies. The review consists of integrative and updated information on the potential traditional medicines against COVID-19 and will facilitate researchers to develop traditional medicines for the management of COVID-19.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Topics:
Traditional medicine
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
J.sajb.2022.04.053
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