Post Mucormycosis Frontal Bone Osteonecrosis: "A Road Less Traveled During the Pandemic".
World Neurosurg
; 172: e335-e342, 2023 Apr.
Article
in English
| MEDLINE | ID: covidwho-2184408
ABSTRACT
BACKGROUND:
Osteonecrosis in mucormycosis is a rare phenomenon and has been reported usually following trauma or in immunocompromised individuals. Osteonecrosis of skull as a complication of mucormycosis is a rare presentation, which makes the study ever so rare and interesting.METHODS:
Within 6 months, a total of 114 patients presented with mucormycosis as COVID-19 sequel, 60 of whom underwent form of endoscopic sinus debridement. Six of these 60 patients presented with frontal bone osteonecrosis and were included in the study. All 6 patients presented within a time period of 2-4 months' post FESS.RESULTS:
One of the 6 patients succumbed to her illness. Another patient presented with local recurrence after 3 months, for which she underwent resurgery and debridement. The other 4 patients showed gradual recovery and are without symptoms or radiologic progression at 6-month follow-up.CONCLUSIONS:
Osteonecrosis in mucormycosis is a rare phenomenon, and the 2 entities have rarely been reported together. The disease usually limits itself to the frontal bone only, and pathogenesis for spread is due to a vicious cycle of infection and ischemia. Prompt diagnosis via imaging, aggressive surgical debridement with a good antifungal cover, good patient compliance, and regular follow-up form the mainstay of treatment.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Osteonecrosis
/
COVID-19
/
Mucormycosis
Type of study:
Case report
/
Cohort study
/
Diagnostic study
/
Prognostic study
Topics:
Long Covid
Limits:
Female
/
Humans
Language:
English
Journal:
World Neurosurg
Journal subject:
Neurosurgery
Year:
2023
Document Type:
Article
Affiliation country:
J.wneu.2023.01.023
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