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Preclinical characterization and anti-SARS-CoV-2 efficacy of ATV014: an oral cyclohexanecarboxylate prodrug of 1'-CN-4-aza-7,9-dideazaadenosine C-nucleoside.
Zhou, Qifan; Yang, Sidi; Cao, Liu; Yang, Yang; Xu, Tiefeng; Chen, Qishu; Lu, Hongzhou; Li, Yingjun; Guo, Deyin; Zhang, Xumu.
  • Zhou Q; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Academy for Advanced Interdisciplinary Studies and Medi-X Pingshan, Southern University of Science and Technology, Shenzhen, Guangdong, 518000, China.
  • Yang S; Centre for Infection and Immunity Studies (CIIS), School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
  • Cao L; Guangzhou Laboratory, Bio-Island, Guangzhou, China.
  • Yang Y; Centre for Infection and Immunity Studies (CIIS), School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
  • Xu T; Shenzhen Key Laboratory of Pathogen and Immunity, National Clinical Research Center for infectious disease, State Key Discipline of Infectious Disease, Shenzhen Third People's Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen, China.
  • Chen Q; Centre for Infection and Immunity Studies (CIIS), School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 518107, China.
  • Lu H; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Academy for Advanced Interdisciplinary Studies and Medi-X Pingshan, Southern University of Science and Technology, Shenzhen, Guangdong, 518000, China.
  • Li Y; Shenzhen Key Laboratory of Pathogen and Immunity, National Clinical Research Center for infectious disease, State Key Discipline of Infectious Disease, Shenzhen Third People's Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen, China.
  • Guo D; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Academy for Advanced Interdisciplinary Studies and Medi-X Pingshan, Southern University of Science and Technology, Shenzhen, Guangdong, 518000, China. liyj@sustech.edu.cn.
  • Zhang X; Centre for Infection and Immunity Studies (CIIS), School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 518107, China. guodeyin@mail.sysu.edu.cn.
Signal Transduct Target Ther ; 8(1): 27, 2023 01 12.
Article in English | MEDLINE | ID: covidwho-2185775
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Prodrugs / COVID-19 Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2023 Document Type: Article Affiliation country: S41392-023-01310-0

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Prodrugs / COVID-19 Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2023 Document Type: Article Affiliation country: S41392-023-01310-0