Efficacy of chemical disinfectants against SARS-CoV-2 on high-touch surface materials.
J Appl Microbiol
; 2022 Dec 15.
Article
in English
| MEDLINE | ID: covidwho-2262218
ABSTRACT
AIMS:
This study aimed to provide operationally relevant SARS-CoV-2 surface disinfection efficacy information. METHODS ANDRESULTS:
Three EPA-registered disinfectants (Vital Oxide, Peroxide, Clorox Total 360 (C360)) and one antimicrobial formulation (CDC Bleach) were evaluated against SARS-CoV-2 on material coupons and were tested using Spray (no-touch with contact time) and Spray & Wipe (wipe immediately post-application) methods immediately and 2 hours post-contamination. Efficacy was evaluated for infectious virus, with a subset tested for vRNA recovery. Efficacy varied by method, disinfectant and material. CDC Bleach solution showed low efficacy against SARS-CoV-2 (Log Reduction < 1.7), unless applied via Spray & Wipe. Additionally, mechanical wiping increased the efficacy of treatments against SARS-CoV-2. Recovery of vRNA post-disinfection suggested vRNA may overestimate infectious virus remaining.CONCLUSIONS:
Efficacy depends on surface material, chemical, and disinfection procedure, and suggests that mechanical wiping alone has some efficacy at removing SARS-CoV-2 from surfaces. We observed that disinfectant treatment biased recovery of vRNA over infectious virus.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
Language:
English
Journal subject:
Microbiology
Year:
2022
Document Type:
Article
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