Your browser doesn't support javascript.
Efficacy of chemical disinfectants against SARS-CoV-2 on high-touch surface materials.
Hardison, Rachael L; Nelson, Sarah W; Limmer, Rebecca; Marx, Joel; Taylor, Brian M; James, Ryan R; Stewart, Michael J; Lee, Sang Don D; Calfee, M Worth; Ryan, Shawn P; Howard, Megan W.
  • Hardison RL; Battelle Memorial Institute, Columbus, OH.
  • Nelson SW; Battelle Memorial Institute, Columbus, OH.
  • Limmer R; Battelle Eastern Science & Technology Center, Aberdeen, MD.
  • Marx J; Battelle Eastern Science & Technology Center, Aberdeen, MD.
  • Taylor BM; Battelle Eastern Science & Technology Center, Aberdeen, MD.
  • James RR; Battelle Memorial Institute, Columbus, OH.
  • Stewart MJ; U.S. EPA, Durham, NC.
  • Lee SDD; U.S. EPA, Durham, NC.
  • Calfee MW; U.S. EPA, Durham, NC.
  • Ryan SP; U.S. EPA, Durham, NC.
  • Howard MW; Battelle Memorial Institute, Columbus, OH.
J Appl Microbiol ; 2022 Dec 15.
Article in English | MEDLINE | ID: covidwho-2262218
ABSTRACT

AIMS:

This study aimed to provide operationally relevant SARS-CoV-2 surface disinfection efficacy information. METHODS AND

RESULTS:

Three EPA-registered disinfectants (Vital Oxide, Peroxide, Clorox Total 360 (C360)) and one antimicrobial formulation (CDC Bleach) were evaluated against SARS-CoV-2 on material coupons and were tested using Spray (no-touch with contact time) and Spray & Wipe (wipe immediately post-application) methods immediately and 2 hours post-contamination. Efficacy was evaluated for infectious virus, with a subset tested for vRNA recovery. Efficacy varied by method, disinfectant and material. CDC Bleach solution showed low efficacy against SARS-CoV-2 (Log Reduction < 1.7), unless applied via Spray & Wipe. Additionally, mechanical wiping increased the efficacy of treatments against SARS-CoV-2. Recovery of vRNA post-disinfection suggested vRNA may overestimate infectious virus remaining.

CONCLUSIONS:

Efficacy depends on surface material, chemical, and disinfection procedure, and suggests that mechanical wiping alone has some efficacy at removing SARS-CoV-2 from surfaces. We observed that disinfectant treatment biased recovery of vRNA over infectious virus.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies Language: English Journal subject: Microbiology Year: 2022 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies Language: English Journal subject: Microbiology Year: 2022 Document Type: Article