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Candidemia in a tertiary care hospital: Epidemiology, speciation and antifungal susceptibility pattern
Medical Mycology ; 60(Supplement 1):62, 2022.
Article in English | EMBASE | ID: covidwho-2189358
ABSTRACT

Objective:

The incidence of bloodstream fungal infection is on the rise and Candida species remains responsible for the majority of the cases. Candidemia is frequently associated with a high rate of mortality and morbidity. The purpose of this study was to characterize Candidemia, its epidemiology, species distribution, and antifungal susceptibility pattern in a tertiary care hospital. Methods and

Material:

Candida species isolated from the blood culture of 51 patients in a tertiary care hospital during the period from 2016 to 2021 were included in the study. The growth on SDA was confirmed by Gram staining and speciation and antifungal susceptibility were performed with Automated system VITEK 2.0. Result(s) Out of51 isolates, Candida auris wasthe most common speciesaccounting for about 37.2% followedby C.albicans 19.7%, C. tropicalis 17.6%, and C. famata 9.8%. Candida auris has emerged as the predominant species during severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) pandemic.The incidence has risen from 22% to 60% during the pandemi C. Candida specieswere foundto be96.08% sensitiveto flucytosine, 94.12% tovoricanazole, 90.19%to casp ofungin/micafungin, 60.78% to amphoterecin B, and 56.86% to fluconazole. Conclusion(s) Candida auris has emerged as the predominant species in ICU setup and during SARS-CoV-2 pandemi C. Empirical treatment with echinocandines would be appropriate in high-risk patients with suspected Candidemia.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Observational study Language: English Journal: Medical Mycology Year: 2022 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Observational study Language: English Journal: Medical Mycology Year: 2022 Document Type: Article