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Reconsideration of Antinucleocapsid IgG Antibody as a Marker of SARS-CoV-2 Infection Postvaccination for Mild COVID-19 Patients.
Dhakal, Santosh; Yu, Tong; Yin, Anna; Pisanic, Nora; Demko, Zoe O; Antar, Annukka A R; Cox, Andrea L; Heaney, Christopher D; Manabe, Yukari C; Klein, Sabra L.
  • Dhakal S; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Yu T; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Yin A; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Pisanic N; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Demko ZO; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Antar AAR; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Cox AL; Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
  • Heaney CD; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Manabe YC; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Klein SL; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Open Forum Infect Dis ; 10(1): ofac677, 2023 Jan.
Article in English | MEDLINE | ID: covidwho-2190085
ABSTRACT
Antinucleocapsid (anti-N) immunoglobulin G antibody responses were lower in plasma and oral fluid after severe acute respiratory syndrome coronavirus 2 infection in vaccinated patients compared with patients infected before vaccination or infected without vaccination. This raises questions about the long-term use of anti-N antibodies as a marker for natural infection for surveillance.
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Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines Language: English Journal: Open Forum Infect Dis Year: 2023 Document Type: Article Affiliation country: Ofid

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Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines Language: English Journal: Open Forum Infect Dis Year: 2023 Document Type: Article Affiliation country: Ofid