COVID-19 as a Trigger of Acute-on-Chronic Hepatitis B Presenting With Undetectable INR Due to Hypercoagulability in a 16-Year-Old Girl.
Pediatr Infect Dis J
; 42(2): 143-145, 2023 02 01.
Article
in English
| MEDLINE | ID: covidwho-2190923
ABSTRACT
In patients with SarS-CoV2 and chronic Hepatitis B (HBV) co-infection liver injury is associated with a worse prognosis. We report a case of acute chronic liver failure (ACLF) with encephalopathy due to HBV reactivation during COVID-19 with undetectable INR. Thromboelastography showed a profile consistent with a prothrombotic state so INR was not a reliable marker of liver function until plasma infusion. After plasma infusion, indeed, an imbalance of hepatic function was shown by an underlying INR prolongation that was consistent with an ACLF.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Hepatitis B, Chronic
/
Thrombophilia
/
Acute-On-Chronic Liver Failure
/
COVID-19
/
Hepatitis B
Type of study:
Case report
/
Prognostic study
Topics:
Long Covid
Limits:
Adolescent
/
Female
/
Humans
Language:
English
Journal:
Pediatr Infect Dis J
Journal subject:
Communicable Diseases
/
Pediatrics
Year:
2023
Document Type:
Article
Affiliation country:
Inf.0000000000003771
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