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Assessing Trustworthy AI in Times of COVID-19: Deep Learning for Predicting a Multiregional Score Conveying the Degree of Lung Compromise in COVID-19 Patients.
Allahabadi, Himanshi; Amann, Julia; Balot, Isabelle; Beretta, Andrea; Binkley, Charles; Bozenhard, Jonas; Bruneault, Frederick; Brusseau, James; Candemir, Sema; Cappellini, Luca Alessandro; Chakraborty, Subrata; Cherciu, Nicoleta; Cociancig, Christina; Coffee, Megan; Ek, Irene; Espinosa-Leal, Leonardo; Farina, Davide; Fieux-Castagnet, Genevieve; Frauenfelder, Thomas; Gallucci, Alessio; Giuliani, Guya; Golda, Adam; van Halem, Irmhild; Hildt, Elisabeth; Holm, Sune; Kararigas, Georgios; Krier, Sebastien A; Kuhne, Ulrich; Lizzi, Francesca; Madai, Vince I; Markus, Aniek F; Masis, Serg; Mathez, Emilie Wiinblad; Mureddu, Francesco; Neri, Emanuele; Osika, Walter; Ozols, Matiss; Panigutti, Cecilia; Parent, Brendan; Pratesi, Francesca; Moreno-Sanchez, Pedro A; Sartor, Giovanni; Savardi, Mattia; Signoroni, Alberto; Sormunen, Hanna-Maria; Spezzatti, Andy; Srivastava, Adarsh; Stephansen, Annette F; Theng, Lau Bee; Tithi, Jesmin Jahan.
  • Allahabadi H; Enterprise Intelligence DepartmentEY Netherlands 1083 HP Amsterdam The Netherlands.
  • Amann J; Health Ethics and Policy LabDepartment of Health Sciences and TechnologyETH Zurich 8092 Zürich Switzerland.
  • Balot I; Postgraduate Studies in Diplomacy and International RelationsCenter for Diplomatic & Strategic Studies 75015 Paris France.
  • Beretta A; Institute of Information Science and Technologies, National Research Council of Italy (CNR) 56124 Pisa Italy.
  • Binkley C; Bioethics CenterHackensack Meridian Health Edison NJ 08820 USA.
  • Bozenhard J; Faculty of PhilosophyUniversity of Oxford Oxford OX2 6GG U.K.
  • Bruneault F; Philosophie DepartmentCollège André- Laurendeau Montreal QC H8N 2J4 Canada.
  • Brusseau J; École des médiasUniversité du Québec à Montréal Montreal QC H2L 2C4 Canada.
  • Candemir S; Philosophy DepartmentPace University New York NY 10038 USA.
  • Cappellini LA; Wexner Medical CenterDepartment of RadiologyThe Ohio State University Columbus OH 43210 USA.
  • Chakraborty S; Department of RadiologyHumanitas Research Hospital 20089 Milan Italy.
  • Cherciu N; Department of Biomedical SciencesHumanitas University 20089 Milan Italy.
  • Cociancig C; Faculty of Science, Agriculture, Business and LawUniversity of New England Armidale NSW 2351 Australia.
  • Coffee M; Faculty of Engineering and Information TechnologyUniversity of Technology Sydney Sydney NSW 2007 Australia.
  • Ek I; European Centre of Excellence on the Regulation of Robotics & AIScuola Superiore Sant'Anna 56127 Pisa Italy.
  • Espinosa-Leal L; Group of Computer ArchitectureUniversity of Bremen 28359 Bremen Germany.
  • Farina D; Department of MedicineDivision of Infectious Diseases and ImmunologyNew York University Grossman School of Medicine New York NY 10016 USA.
  • Fieux-Castagnet G; AI Research SectionDigital Institute 16731 Stockholm Sweden.
  • Frauenfelder T; Department of Business Management and AnalyticsArcada University of Applied Sciences 00550 Helsinki Finland.
  • Gallucci A; Department of Medical and Surgical SpecialtiesRadiological Sciences, and Public HealthUniversity of Brescia 25121 Brescia Italy.
  • Giuliani G; Ethique GroupeSNCF Reseau SA 93418 La Plaine France.
  • Golda A; Institute of Diagnostic and Interventional Radiology, University Hospital Zurich 8091 Zürich Switzerland.
  • van Halem I; Department of Mathematics and Computer ScienceEindhoven University of Technology 5600 MB Eindhoven The Netherlands.
  • Hildt E; Data Privacy Advisor, Ericsson 11331 Stockholm Sweden.
  • Holm S; Department of Cardiology4th Gliwice Municipal Hospital 44-100 Gliwice Poland.
  • Kararigas G; Z-Inspection® Initiative Frankfurt Germany.
  • Krier SA; Center for the Study of Ethics in the ProfessionsIllinois Institute of Technology Chicago IL 60616 USA.
  • Kuhne U; Department of Food and Resource EconomicsUniversity of Copenhagen 1165 Copenhagen Denmark.
  • Lizzi F; Department of PhysiologyFaculty of MedicineUniversity of Iceland 101 Reykjavik Iceland.
  • Madai VI; Cyber Policy CenterStanford University Stanford CA 94305 USA.
  • Markus AF; Department for DermatologyHautmedizin Bad Soden 65812 Bad Soden Germany.
  • Masis S; Data Science DepartmentScuola Normale Superiore 56126 Pisa Italy.
  • Mathez EW; Charité Lab for Artificial Intelligence in MedicineDepartment of Neurosurgery, the QUEST Centre for Responsible ResearchBerlin Institute of Health at Charité, Charité Universitätsmedizin Berlin 10117 Berlin Germany.
  • Mureddu F; Faculty of Computing, Engineering and the Built Environment, School of Computing and Digital TechnologyBirmingham City University Birmingham B4 7XG U.K.
  • Neri E; Department of Medical InformaticsErasmus University Medical Center 3015 GD Rotterdam The Netherlands.
  • Osika W; CADS DepartmentSyngenta Research Triangle Park NC 27709 USA.
  • Ozols M; Z-Inspection® Initiative Frankfurt Germany.
  • Panigutti C; Policy ResearchThe Lisbon Council 1040 Brussels Belgium.
  • Parent B; Department of Translational ResearchAcademic RadiologyUniversity of Pisa 56126 Pisa Italy.
  • Pratesi F; Center for Psychiatry ResearchDepartment of Clinical NeuroscienceKarolinska Institutet 171 77 Stockholm Sweden.
  • Moreno-Sanchez PA; Department of MedicineThe University of Cambridge, Addenbrooke's Hospital Cambridge CB2 0QQ U.K.
  • Sartor G; School of Cell Matrix and Regenerative MedicineThe University of Manchester Manchester M13 9PG U.K.
  • Savardi M; Department of Human GeneticsThe Wellcome Sanger Institute, Wellcome Genome Campus Cambridge CB10 1RQ U.K.
  • Signoroni A; Department of Computer ScienceUniversity of Pisa 56127 Pisa Italy.
  • Sormunen HM; Division of Medical EthicsDepartment of Population HealthNYU Grossman School of Medicine New York NY 10016 USA.
  • Spezzatti A; Institute of Information Science and Technologies, National Research Council of Italy (CNR) 56124 Pisa Italy.
  • Srivastava A; School of Healthcare and Social WorkSeinäjoki University of Applied Sciences 60100 Seinäjoki Finland.
  • Stephansen AF; Law DepartmentEuropean University Institute 50139 Firenze Italy.
  • Theng LB; CIRSFID-Alma AI and Law DepartmentUniversity of Bologna 40121 Bologna Italy.
  • Tithi JJ; Department of Information EngineeringUniversity of Brescia 25121 Brescia Italy.
IEEE Trans Technol Soc ; 3(4): 272-289, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2192118
ABSTRACT
This article's main contributions are twofold 1) to demonstrate how to apply the general European Union's High-Level Expert Group's (EU HLEG) guidelines for trustworthy AI in practice for the domain of healthcare and 2) to investigate the research question of what does "trustworthy AI" mean at the time of the COVID-19 pandemic. To this end, we present the results of a post-hoc self-assessment to evaluate the trustworthiness of an AI system for predicting a multiregional score conveying the degree of lung compromise in COVID-19 patients, developed and verified by an interdisciplinary team with members from academia, public hospitals, and industry in time of pandemic. The AI system aims to help radiologists to estimate and communicate the severity of damage in a patient's lung from Chest X-rays. It has been experimentally deployed in the radiology department of the ASST Spedali Civili clinic in Brescia, Italy, since December 2020 during pandemic time. The methodology we have applied for our post-hoc assessment, called Z-Inspection®, uses sociotechnical scenarios to identify ethical, technical, and domain-specific issues in the use of the AI system in the context of the pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study Language: English Journal: IEEE Trans Technol Soc Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study Language: English Journal: IEEE Trans Technol Soc Year: 2022 Document Type: Article